Poultry:

Preventive and therapeutic treatment of Colisepticemi, Salphingitis, Colera, Coryza and Staphylococ infections

Lambs and Calves:

Preventive and therapeutic treatment of diare due to bacterial infections, gastroenteritis, Colisepticemi, bronchopneumonia, diphteria and omphalitis

 

USAGE AND DOSAGE 

Pharmacological dose is 24-30 mg/kg.

In lambs, goats and calves therapeutic dose is 1 ml MEDSUTI/ 5kg bw. Administered with drinking water. Daily dose to be divided into two doses is recommended. Treatment period is 3-5 days.

In chickens and turkeys therapeutic dose is 200-250 ml/1000 kg. Administered with drinking water. Medicated water should be prepared fresh and daily.

 

WITHDRAWAL PERIOD

Meat:

Poultry: 10 days

Goat, lambs, calves: 14 days

WARNINGS

“Not for human use.” “Keep out of reach of children.”

 

STORING AND SHELF LIFE

Store in room temperature, keep away from humidity and light. Shelf life 2 years.

Sulfachloropyridazine is an antibiotic belonging to the group of sulfonamides. Like all sulfonamides, sulfachloropyridazine is a competitive antagonist of para-aminobenzoic acid (PABA), a precursor of folic acid, in protozoa and bacteria. Trimethoprim is an antibacterial diaminopyrimidine derivate that synergises with sulfonamides in the inhibition of bacterial replication. It blocks tetrahydrofolate production at a different biosynthetic site than sulfonamides, therefore, the combination of both drugs is more effective at lower concentrations than either drug used alone.

Mainly susceptible microorganisms to Sulfonamides+trimetophrim combinations are:

– Gram positive aerobes: Staphylococcus aureus, Streptococcus spp., Actinomyces spp., Corynebacterium spp., Listeria monocytogenes, Erysipelothrix rhusiopathie,

– Gram negative aerobes: Enterobacteriaceae (E.coli, Salmonella spp., Klebsiella spp., Proteus spp., Yersinia spp.), Pasteurella spp., Haemophilus spp., Actinobacillus spp., Bordetella spp.,

– Anaerobes: Clostridium spp., Bacteroides spp., Fusobacterium spp., Chlamydia spp., Actinomyces spp.,

The microorganisms which have medium level susceptibity include some of Mycobacterium spp and, some Nocardia spp.

Rickettsia spp., Leptospira spp., Pseudomanas aeroginosa, Mycoplasma spp. Are known as resistant.